UV PROTECTION IN THE CORNEA: FAILURE AND RESCUE

UV Protection in the Cornea: Failure and Rescue

Ultraviolet (UV) irradiation induces DNA lesions in all directly exposed tissues.In the human body, two tissues are chronically exposed to UV: the skin and the cornea.The most frequent UV-induced DNA lesions are cyclobutane pyrimidine dimers (CPDs) that can lead to apoptosis or induce tumorigenesis.Lacking the protective pigmentation of the skin, t

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